Friday, 27 April 2012

In Vitro Maturation(IVM)-A Remarkable Fertility Treatment

This remarkable fertility treatment was developed to provide a safer, healthier and cheaper alternative to conventional IVF. Improved IVM techniques are developing very fast and an increasing number of fertility clinics are offering IVM. The concept of IVM technology remains attractive.

In vitro maturation involves harvesting immature or unripe eggs from a woman. Hormone treatments are administered to the eggs in a laboratory procedure in order to cause those eggs to mature so they may be fertilized. The fertilized eggs are then put back into the uterus.
In vitro maturation is similar to IVF in that fertilized eggs are implanted to help a woman become pregnant. However, in vitro maturation involves harvesting unripe eggs, as opposed to IVF, which requires forced maturation of the eggs in the uterus.
Immature eggs are collected from unstimulated or minimally stimulated ovaries under ultrasound scan guidance. The immature eggs are then matured in the laboratory for 24-48 hours using culture medium with added small quantities of hormones. Intracytoplasmic sperm injection (ICSI) is used for fertilization of the matured eggs. The resulting embryos are transferred to the women's wombs.

Who would benefit from IVM treatment?
A number of people may benefit from IVM treatment:
  • As an alternative to IVF for women with PCOS(The condition, polycystic ovarian syndrome, known as PCOS, is a common condition and is the commonest cause of ovulation disorders in women of reproductive age) ; these patients are at significant risk of OHSS
  • As an alternative to IVF for younger women with normal menstrual cycles, IVM being less costly and safer
  • Fertility preservation in young cancer women who are going to receive chemotherapy or radiotherapy
  • Salvaging immature eggs collected during a standard IVF/ICSI (when unexpectedly a significant number of eggs collected are immature)
  • Women who will benefit most from in vitro maturation are women aged 35 and younger and have antral follicle count of 10 or more.
The difference between IVM and conventional in vitro fertilisation (IVF) is that the eggs are immature when they are collected. This means that the woman does not need to take as many drugs before the eggs can be collected as it might if using conventional IVF, when mature eggs are collected.

IVM is being more reliable and assuring at Srishti Assisted Fertility and Advanced Laparoscopy (SAFAL) ,Puducherry ,with an affordable packages.

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